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Tamehisa Tetsuro

Affiliate Master Yamaguchi University

Effects of female hormone withdrawal and ulipristal acetate on MED12 mutation positive and negative uterine leiomyomas using a xenograft model.

Scientific reports Volume 15
published_at 2025-11-14
s41598-025-23721-5.pdf
[fulltext] 3.08 MB
Supplemental Data : https://public.oa.kenkyu.yamaguchi-u.ac.jp/41aca251-9955-463e-9b47-ba073689ad15
Title
Effects of female hormone withdrawal and ulipristal acetate on MED12 mutation positive and negative uterine leiomyomas using a xenograft model.
Creators Sato Shun
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Sakai Takahiro
Creators Tamehisa Tetsuro
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Shiroshita Amon
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Takasaki Hitomi
Creators Kajimura Takuya
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Tamura Isao
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Maekawa Ryo
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Sugino Norihiro
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Source Identifiers [EISSN] 2045-2322
Creator Keywords
Uterine leiomyomas Xenograft models Female hormones Ulipristal acetate MED12 mutation Smooth muscle cells
Languages eng
Resource Type journal article
Publishers Springer Nature
Date Issued 2025-11-14
Rights
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International(https://creativecommons.org/licenses/by-nc-nd/4.0/)
© The Author(s) 2025()
File Version Version of Record
Access Rights open access
Relations
[isIdenticalTo] 10.1038/s41598-025-23721-5
[isSupplementedBy] [URI]https://public.oa.kenkyu.yamaguchi-u.ac.jp/41aca251-9955-463e-9b47-ba073689ad15
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Pathophysiology of uterine leiomyomas grown in a female hormone-independent manner using single-cell analysis 24K12533
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Clarifying the ptathogenesis of decidualization failure using a novel human in vitro implantation model 24K12579
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Heme oxygenase1発現抑制と三酸化二砒素を用いた子宮頸癌の新規治療法の開発 24K12626
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award 独自の改良型子宮内膜オルガノイドを応用した着床機構および着床不全の病態の解明 23K27734
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Study for the mechanisms of uterine fibroid development and its diversity from the view of microenvironment using single cell analysis 22K19603