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Iida Yasuhiko

Affiliate Master Yamaguchi University

Intraoperative anaphylactic shock related to fibrin glue application during video-assisted thoracoscopic surgery

山口医学 Volume 69 Issue 3 Page 141-144
published_at 2020-09-25
B030069000304.pdf
[fulltext] 1.33 MB
Title
胸腔鏡手術中にフィブリン糊によるアナフィラキシーショックを来たした1例
Intraoperative anaphylactic shock related to fibrin glue application during video-assisted thoracoscopic surgery
Creators Yano Yuka
Creators Kuga Takayuki
Creators Sakamoto Ryuunosuke
Creators Shigeta Masatoshi
Creators Iida Yasuhiko
Source Identifiers
Creator Keywords
フィブリン糊 アナフィラキシーショック 胸腔鏡手術
フィブリン糊は出血箇所の閉鎖や臓器創傷部の接着など外科手術で広く用いられている.胸腔鏡手術中にフィブリン糊によるアナフィラキシーショックを来たした症例を経験したので報告する.症例は83歳女性.右肺癌(cStageⅠA1)疑いで診断,治療目的に胸腔鏡下肺部分切除術が施行された.肺の切離断端からエアリークを認めたため,ボルヒール®を塗布したところ数分以内に急激な血圧低下,全身性紅班がありフィブリン糊によるアナフィラキシーショックが疑われた.カテコラミン投与と輸液負荷にてショック状態を離脱することができた.また原因と考えられるフィブリン糊の除去と胸腔内洗浄も有効であった.フィブリン糊など生物学的製剤を使用する際は副作用としてアナフィラキシーショックに注意する必要がある.
Fibrin glue is used across most surgical specialties. We report a case of anaphylactic shock attributable to intraoperative fibrin glue application. An 83-year-old woman with suspected primary lung cancer(clinical stage IA)underwent video-assisted partial resection of the right upper lobe. She developed air leakage after the procedure, and fibrin glue was applied to seal the site of leakage. The patient showed a sudden reduction in blood pressure and developed skin rash within a few minutes, which were attributable to fibrin glue-induced anaphylactic shock. She was immediately treated with rapid infusion and catecholamine administration. We removed as much of the fibrin glue as possible, resulting in improvement in her general condition. Clinicians should be aware that intraoperative use of biological tissues can precipitate anaphylactic shock.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 2020-09-25
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 大学院医学系研究科(医学)