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Ohama Takashi

Affiliate Master Yamaguchi University

PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells

Journal of Biological Chemistry Volume 300 Issue 1 Page 1-11
published_at 2023-12-22
1-s2.0-S0021925823026121-main.pdf
[fulltext] 1.87 MB
Supplemental Data : https://public.oa.kenkyu.yamaguchi-u.ac.jp/d4f57788-62e5-4968-a93f-e09d32ee803b
Title
PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells
Creators Kohyanagi Naoki
Creators Kitamura Nao
Creators Ikeda Shunta
Creators Shibutani Shusaku
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Sato Koichi
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Ohama Takashi
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Source Identifiers [PISSN] 0021-9258 [EISSN] 1083-351X
Languages eng
Resource Type journal article
Publishers Elsevier Inc
Date Issued 2023-12-22
Rights
© 2023 THE AUTHORS. Published by Elsevier Inc on behalf of American Society for Biochemistry and Molecular Biology. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).()
Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)
File Version Version of Record
Access Rights open access
Relations
[isIdenticalTo] https://doi.org/10.1016/j.jbc.2023.105584
[isSupplementedBy] [URI]https://public.oa.kenkyu.yamaguchi-u.ac.jp/d4f57788-62e5-4968-a93f-e09d32ee803b
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Stemness as a target for anti-cancer drug development 20H03151
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Understanding the pathogenic mechanism of NASH by focusing on the conversion of methionine metabolism to phosphorylation signals 22K19249
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award UndruggableなMYCを標的とした抗がん戦略創出のための基盤的研究 23H02384
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award がん幹細胞性の発生・維持に、細胞密度は関与するのか? 22J23055