Txnip deficiency causes a susceptibility to acute cold stress with brown fat dysfunction in mice.

Creators Zou Meng

Creators Tanabe Katsuya

Creators Shiinoki Kikuko

Creators Kohno Daisuke

Creators Kagawa Syota

Creators Shirasawa Hideki

Creators Ikeda Kenji

Creators Taguchi Akihiko

Creators Ohta Yasuharu

Creators Okuya Shigeru

Creators Yamada Tetsuya

Creators Kitamura Tadahiro

Creators Masutani Hiroshi

Creators Tanizawa Yukio

Creative Commons Attribution 4.0 International(https://creativecommons.org/licenses/by/4.0/)

[isIdenticalTo] 10.1016/j.jbc.2025.108293

[isSupplementedBy] [URI]https://public.oa.kenkyu.yamaguchi-u.ac.jp/471f7278-6ded-4017-9131-3b6c25deb177

Award The elucidation of the mechanisms underlying beta cell dedifferentiation and plasticity in diabetes [Crossref Funder] https://doi.org/10.13039/501100001691 16K09752

Award The elucidation of Txnip-dependent mechanisms in pancreatic beta cell dedifferentiation leading diabetes [Crossref Funder] https://doi.org/10.13039/501100001691 20K08887

Award The elucidation of pathogenesis of beta cell plasticity associated with dedifferentiation in diabetes mellitus [Crossref Funder] https://doi.org/10.13039/501100001691 23K08011

Award Elucidation of the mechanism of pancreatic alfa cell mass increase and white adipocyte browning induced by a low-carbohydrate/high-protein diet [Crossref Funder] https://doi.org/10.13039/501100001691 18K08516

Award Elucidation of pancreatic alpha cell neogenesis and metabolic regulation via inter-organ networks [Crossref Funder] https://doi.org/10.13039/501100001691 21K08581

Award Elucidation of the mechanism underlying pancreatic a cell (glucagon secretion) impairment in type 2 diabetes [Crossref Funder] https://doi.org/10.13039/501100001691 22H03125

Award From Cellular Stress to beta-cell failure and insulin resistance: Investigation of new mechanisms [Crossref Funder] https://doi.org/10.13039/501100001691 19H03710