赤血球及び臓器中のSuperoxide Dismutase活性に及ぼす有機溶剤の影響

Effects of Organic Solvents on Superoxide Dismutase Activities in Erythrcoytes and Organs of Dog

Creators Hobara Tatsuya

Creators Kobayashi Haruo

Creators Iwamoto Susumu

Creators Higashihara Eiji

Creators Hirota Seiro

Creators Kawamoto Toshihiro

Creators Shimazu Wataru

Creators Sakai Tsunemi

Changes in superoxide desmutase (SOD) activities in erythroeytes and organs of dogs were investigated after administration of six kinds of organic solvents, 1,1,1-trichloroethane, 1,1,2-trichloroethane, triehloroethylene, tetrachloroethylene, toluene, and m-xylene. The reaults obtained were as follows. 1. The SOD activities in erythrocytes were not changed after administration of any solvents. 2. The levels of SOD activities in the organs were decreased by the each of chlorinated organic solvents and the degree of effects were varied by the kind of solvents or organs. 3. Toluene and m-xylene did not decreased the SOD activities in organs.

[ISSN]0513-1731

[NCID]AN00243156