放射線治療を施行したIIIA期（N2）非小細胞肺癌の検討

Clinical studies for clinical stage III A (N2) non-resected non-small cell lung cancer administered radiation therapy

Creators Suda Hiroki

Creators Matsumoto Tsuneo

Creators Hirose Takao

Creators Ebe Kazuyu

Creators Nishigauchi Kazuya

Creators Miura Gouji

Creators Honma Yutaka

Creators Honjou Kazumitsu

Creators Tanaka Nobuyuki

Creators Nakanishi Takashi

Creators Fukuyama Masaru

Creators Oakamoto Yasusada

Creators Suga Kazyyoshi

Creators Nakamura Hiroshi

Forty patients with non-resected non-small cell lung cancer (Clinical Stage III A, N2) administered radiation therapy (RT) were evaluated. All cases were treated by definite radiation dose, over 50gy. In these patients, 17 were treated with RT alone, and 23 with RT and systemic chemotherapy (CT). In RT＋CT group, cis-plutinum (CDDP) was administered for 16 patients. The median survival time of overall patients from initiation of RT was 13 months. Primary response rate was 65%, and survival was higher in response group than non response group (P＜0.05). Among 36 patients with perfprmance status 0 or 1, no significant differences in survival rate were observed among patients with different histological types. However, survival was higher with RT＋CT (with CDDP) than with other therapies (P＜0.05). Therefore, we consider that RT＋CT (with CDDP) is a useful method in this stage.

[ISSN]0513-1731

[NCID]AN00243156