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Matsuzaki Masanori

Affiliate Master Yamaguchi University

Effects of left atrialadistension with exercise on α-human atrial natriuretic peptide(α-hANO) and relationship between α-hANP and exercise capacity

山口医学 Volume 40 Issue 5 Page 517-523
published_at 1991-10
Title
運動負担による心房性利尿ペプチと左心房径の変化および運動耐容能との関係について
Effects of left atrialadistension with exercise on α-human atrial natriuretic peptide(α-hANO) and relationship between α-hANP and exercise capacity
Creators Haraguchi Masahiko
Creators Yamagishi Takashi
Creators Saiki Atsushi
Creators Seto Fumio
Creators Furutani Yuji
Creators Matsuda Masako
Creators Ozaki Masaharu
Creators Matsuzaki Masunori
Creators Kusukawa Reizo
Source Identifiers
To assess the effects of left atrial distension with exercise on α-hANP and to evaluate the relationship between α-hANP and exercise tolerance, cardiopulmonary exercise testing was performed in 23 patients with prior myocardial infarction. The patients exercise on a bicycle ergometry until their exhausion. Left atrial diameter (LAD) increased significantly (P<0.01) from 31.4±6.4 to 33.3±7.8mm, and α-hANP also increased significantly (p<0.001) from 84±51 to 129±75pg/ml. Increments of LAD with exercise by LAD at rest (%Δ LAD) were positively sorrelated with changes in α-hANP (Δ α-hANP)(r=0.43, p<0.05). There was a negative correlation between peak V^^・_<O_2> and α-hANP after exercise (r=-0.45, p<0.05). Anaerbic threshold (AT) was also negatively correlated with α-hANP at rest (r=-0.52, p<0.02) and after exercise (r=-0.56, p<0.01). These indicate that exercise capacity is impaired in patients whose levels of α-hANP are elevated. Thus, left atrial distension may stimulate secreation of α-hANP. Cardiac patients with low exercise capacity have increased α-hANP before and after exercise.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1991-10
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部