脾原発悪性リンパ腫の一例

A Case of Primary Splenic Malignant Lymphoma

Creators Matsuoka Koji

Creators Yahara Noboru

Creators Ueno Tomio

Creators Hazama Syoichi

Creators Tangoku Akira

Creators Oka Masaaki

Creators Akiyama Masaru

Creators Kamei Shinji

Creators Sato Yutaka

Creators Oka Yoshitomo

Primary splenic malignant lymphoma (PSML) is a relatively rare entity: to date about 1 50 cases have been reported in Japan. We reported a case of PSML which occurred in a patient with hepatitis B virus infection. A 52-year-old man was accidentally diagnosed as having a high level of serum LDH, and hypoechoic tumors of the spleen by ultrasonography, conducted during a follow-up survey for chronic hepatitis. Enhanced CT revealed low density masses, and 67Ga scintigraphy revealed hot spots in the spleen. Based on these findings, the patient was diagnosed as having a PSML and underwent a laparoscope-assisted splenectomy. On cross section of the resected specimen, two yellowish white, nodular, and solid tumors were revealed. Histopathologically, these were diffuse, large cell type, B bell malignant lymphoma. According to international classification, the malignant grade corresponded to intermediate, so additional chomotherapy r surgery was performed.

[ISSN]0513-1731

[NCID]AN00243156