Quantitative and morphological studies on the influence of zinc deficiency on the liver of pregnant rats

亜鉛欠乏の妊娠ラット肝臓における定量的および形態学的研究

Creators Mamba Kouichi

Creators Taniguchi Kazuyuki

Creators Kagabu Satoshi

Creators Makita Takashi

The effect of zinc deficiency on trace metals in the liver, spleen, kidney, pancreas and duodenum was investigated in the control and zinc-deficient rate at 17 days and 20 days of pregnancy. Zinc-deficient rats fell into limosis after 5 days of pregnancy. The contents of zinc, iron, copper and manganese in the maternal tissues were measured by colorimetry with 5NPPF. The morphological changes of the liver were observed by light and electron microscopy. The contents of zinc in the pancreas and duodenum were less in the zinc-deficient group than in the control at both 17 days and 20 days of pregnancy. The contents of the copper and manganese in the liver, kidney, pancreas, duodenum and spleen, however, were not significantly different from the control. The contents of iron in the liver, spleen and kidney in the deficient group increased greatly at 17 days and 20 days of pregnancy compared with the control group. The combination rate of transferrin with iron also increased significantly in the deficient group. Staining with Berlin blue or Turnbull's blue showed intense reaction to iron around the interlobular connective tissue of the liver in the zinc deficient group at 20 days

[ISSN]0021-5295

[NCID]AA10521639

[isVersionOf] [URI]http://www.journalarchive.jst.go.jp/japanese/jnltop_ja.php?cdjournal=jvms1939