Synthesis and cycloaddition reaction of 2a, 4, 5-triazabenz[cd]azulene derivatives

Creators Abe Noritaka

Creators Gomi Atsuko

2a, 4, 5-triazabenz[cd]azulene derivatives (2) were synthesized by the reaction of 8-hydrazino-3-phenyl-1-azaazulenes (1) with triethyl orthoformate. 2-chloro substituted compound (2b) was easily hydrolized on silica gel and gave (2-chloro-8-imino-3-phenyl-1-aza-1, 8-dihydroazulen-1-yl)formaldehyde oxime. Reaction of 2a with dimethyl acetylenedicarboxylate gave dimethyl 1-phenyl-2a, 5-diazabenz[cd]azulene-3, 4-dicarboxylate and dimethyl (1-cyano-3-phenyl-1, 8-dihydro-1-azaazulen-8-ylideneamino)maleate.

[ISSN]0385-5414

[NCID]AA00663739