Synthesis and some reactions of 2-amino-1-azaazulene-3-carbaldehyde
Bulletin of the Chemical Society of Japan Volume 65 Issue 2
Page 340-344
published_at 1992
Title
Synthesis and some reactions of 2-amino-1-azaazulene-3-carbaldehyde
Creators
Tanaka Keiko
Creators
Yamagata Satoshi
Creators
Satoh Akira
Creators
Yamane Kameji
2-Chloro-1-azaazulene-3-carbaldehyde (1a) reacted with pyridine, followed by a reacion with piperidine to give 2-amino-1-azaazulene-3-carbaldehyde (1b) in excellent yield. Compound 1b was also obtained by a Vilsmeier?Haack reaction of 2-amino-1-azaazulene. Acetylation of 1b yielded a 2-acetylamino derivative, whereas methylation gave a 1-methylated compound. Reactions of 1b with hydrazines and alkylamines gave the corresponding hydrazones and Schiff bases, respectively, in excellent yields. The reactions of 1b with active methylene compounds gave 1,10-diazabenz[a]azulen-2(1H)-one derivatives. The reaction of 1b with guanidine gave pyrimidine-fuzed 1-azaazulene.
Languages
eng
Resource Type
journal article
Publishers
日本化学会
Date Issued
1992
File Version
Not Applicable (or Unknown)
Access Rights
metadata only access
Relations
[ISSN]0009-2673
[NCID]AA00580132
[isVersionOf]
[URI]http://www.jstage.jst.go.jp/browse/bcsj/-char/en
Schools
大学院医学系研究科（理学）