Changes of gastric mucosal cell kinetics in experimental rat stress ulcer : application of flow cytometry
山口医学 Volume 37 Issue 6
Page 451-457
published_at 1988-12
Title
ラット水侵拘束ストレス潰瘍における胃粘膜細胞動態の変化 : flow cytometry 応用の試み
Changes of gastric mucosal cell kinetics in experimental rat stress ulcer : application of flow cytometry
Creators
Yanai Hideo
Creators
Tada Masahiro
Creators
Karita Mikio
Creators
Oka Shinji
Creators
Matsuda Kazuya
Creators
Okazaki Yukinori
Creators
Takemoto Tadayoshi
Source Identifiers
The Gastric mucosal cell cycle is one of the important gastric mucosal defensive factors. We studied the changes of gastric mucosal cell kinetrics in experimental stress ulcer not only by the usual bromodeoxyuridine (BrdUrd) labelling method to detect the generative cells but by flow cytometry to calculate the S phase cell ratio. S phase cell ratio decreased just after stress load no BrdUrd labelled cell was detected in ulcerative lesions. It is suspected that, the decreased cell cycle speed may be responsible for the pathogenesis of stress ulcer. At 48 hours after the stress load was completed, that S phase ratio increased more than control. It was considered to be regenerative change.
Languages
jpn
Resource Type
journal article
Publishers
山口大学医学会
Date Issued
1988-12
File Version
Not Applicable (or Unknown)
Access Rights
metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools
医学部