Changes of Glutathione S-transferase during Initiation and Promotion of Hepatocarcinogenesis in Rats

published_at 1984-12

Title

ラット肝発癌過程におけるgluathione S-transferaseの動態 : initiationとpromotionの過程において

Creators Ogino Masaaki

Source Identifiers

The activities of glutathione S-transferase (GST) in rat liver cytosol were investigated sequentially during initiation and promotion of hepatocarcinogenesis by means of the experimental model of Solt and Farber. The results suggested that both diethylnitrosamine and 2 -fluorenylacetamide induced the activity of GST. It was also found that the induced enzymic levels of GST were suppressed by partial hepatectomy and was considered that the suppression of GST was a reasonable phenomenon to hepatocarcinogenesis.

Subjects

医学 ( Other)

Languages jpn

Resource Type journal article

Publishers 山口大学医学会

Date Issued 1984-12

File Version Not Applicable (or Unknown)

Access Rights metadata only access

Relations

[ISSN]0513-1731

[NCID]AN00243156

Schools 医学部