Introduciton of acetoxyl group in tropone and azulene nuclei using palladium (II) Acetate : reactions of 2-aminotropones and azulenes with palladium (II) acetate
Chemical & pharmaceutical bulletin Volume 39 Issue 7
Page 1843-1845
published_at 1991
Title
Introduciton of acetoxyl group in tropone and azulene nuclei using palladium (II) Acetate : reactions of 2-aminotropones and azulenes with palladium (II) acetate
Creators
Saito Katsuhiro
Creators
Kozaki Masatoshi
Creators
Uenishi Kazuya
Creators
Takahashi Kensuke
Creator Keywords
acetoxylation
phenylation
2-aminotropone
azulene
palladium acetate
Reactiond of 2-(N, N-dimethylamino)- and 2-(N, N-diethylamino)tropones with palladium (II) acetate in benzene in the presence of sodium acetate afforded the corresponding 7-acetoxylated 2-aminotropones. A similar acetoxylation reaction proceeded with azulene to give 1-acetoxy- and 1, 3-diacetoxyazulenes. On the other hand, phenylation at the 7-position occurred in the reaciton using 2-(N-methyl)anilinotoropone. The acetoxylations are considered to proceed through radical cation complexes formed through oxidation of amino groups by palladium.
Languages
eng
Resource Type
journal article
Publishers
日本薬学会
Date Issued
1991
File Version
Not Applicable (or Unknown)
Access Rights
metadata only access
Relations
[ISSN]0009-2363
[NCID]AA00602100
Schools
大学院医学系研究科（理学）