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Two Distinct Mechanisms of PP2A Regulation by Methylesterase PME-1 Are Both Essential for Mouse Development

FASEB journal : official publication of the Federation of American Societies for Experimental Biology Volume 39 Issue 9
published_at 2025-05-06
Supplemental Data : https://public.oa.kenkyu.yamaguchi-u.ac.jp/c1512592-2104-4581-8604-9dcda7dad1ac
Title
Two Distinct Mechanisms of PP2A Regulation by Methylesterase PME-1 Are Both Essential for Mouse Development
Creators Ikeda Shunta
Creators Ando Sana
Creators Kishida Nana
Creators Tanaka Keiko
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Sakurai Masashi
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Sakai Yusuke
Creators Ayabe Shinya
Creators Mizuno-Iijima Saori
Creators Yoshiki Atsushi
Creators Nakashima Kenichi
Creators Tsuji Shunya
[e_rad]80898370 1000080898370
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Asagiri Masataka
[e_rad]20372435 1000020372435
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Baba Taiki
Creators Takeda Kohsuke
Creators Sato Koichi
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators Ohama Takashi
Affiliate Master Yamaguchi University
[kakenhi]15501 grid.268397.1
Source Identifiers [PISSN] 0892-6638 [EISSN] 1530-6860
Creator Keywords
Protein methylation Protein phosphatase 2A (PP2A) Protein phosphatase methylesterase-1 (PME-1) Protein-protein interaction (PPI)
Languages eng
Resource Type journal article
Publishers Wiley Federation of American Societies for Experimental Biology
Date Issued 2025-05-06
File Version Accepted Manuscript
Access Rights metadata only access
Relations
[isVersionOf] https://doi.org/10.1096/fj.202402617RR
[isSupplementedBy] [URI]https://public.oa.kenkyu.yamaguchi-u.ac.jp/c1512592-2104-4581-8604-9dcda7dad1ac
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Platform of Supporting Cohort Study and Biospecimen Analysis 16H06277
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Stemness as a target for anti-cancer drug development 20H03151
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award Understanding the pathogenic mechanism of NASH by focusing on the conversion of methionine metabolism to phosphorylation signals. 22K19249
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award UndruggableなMYCを標的とした抗がん戦略創出のための基盤的研究 23H02384
Funding Refs
Japan Society for the Promotion of Science [crossref_funder]https://doi.org/10.13039/501100001691
Award 創薬標的の同定を目指した脂肪肝炎とそれに続発する肝臓がんの分子機構の解明 22KJ2341