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Chemical Identification of Abnormal Hemoglobin A new cord blood hemoglobin Hb F Kogobuki γ6 (A3) Glu → Gly

山口医学 Volume 30 Issue 4 Page 391-400
published_at 1981-12
Title
異常ヘモグロビンの化学的固定新しい胎児型ヘモグロビンHb F Kotobuki γ6 (A3) Glu→Gly
Chemical Identification of Abnormal Hemoglobin A new cord blood hemoglobin Hb F Kogobuki γ6 (A3) Glu → Gly
Creators Yoshinaka Hiroshi
Source Identifiers
We recently found two varient hemoglobin in a survet of 1,970 cord bloods collected in Yamaguchi prefecture. One was a fast moving varient like Hb J and the other a slow moving hemoglobin similar to Hb S. The former proved to be a varient of αchain and the latter that of γ chain by urea polyacrylamide gel electrophoresis of the globin. The γchain varient was purified by DE-52 column chromatography. It emerged between Hb A_2 and Hb A (A_0) and comparised approximately 10% of total hemoglobin or 17% of Hb F. The γ chain was prepared by CM-52 column chromatography and studied by amino acid analysis,…
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1981-12
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部