Ventilation Abnormalities in Obstructive Airways Disorder: Detection with Pulmonary Dynamic Densitometry by Means of Spiral CT Versus Dynarnic Xe-133 SPECT

気道閉塞性肺疾患の換気異常:Spiral computed tomography(spiral CT)による肺dynamic densitometry(PDD)とゼノンガス肺dynamic SPECTによる検出

Ventilation Abnormalities in Obstructive Airways Disorder: Detection with Pulmonary Dynamic Densitometry by Means of Spiral CT Versus Dynarnic Xe-133 SPECT

Creators Suga Kazuyoshi

PURPOSE: The usefulness of pulmonary dynamic densitometry (PDD) acquired by spiral computed tomography (CT) to detect ventilation abnormalities in obstructive airway disorders was evaluated in comparison with dynamic xenon-133 (Xe-133) SPECT. MATERIALS ANTD METHODS : Eight-second, continuous spiral CT scan was performed over 2-3 respiratory cycles in six healthy volunteers, 19 patients with airways disorder, and six patients with restrictive lung disease. The data set were reconstructed as 36 one-second temporarlly overlapping images at 0.2-second intervals, and regional PDD curves were displayed. Regional ventilation was assessed by Xe-133 clearance-time on Xe-133 SPECT. RESULTS: Normal lungs showed smooth, sinusoidal PDD curves with maximal amplitude in lung attenuation change (MALAC) of 54.9 + 24.5 HU

[ISSN]0513-1731

[NCID]AN00243156