Biochemical and histochemical studies on variant γ-glutamyl transpeptidase in human gastric cancer
山口医学 Volume 37 Issue 3
Page 169-174
published_at 1988-06
Title
ヒト胃癌におけるvariant γ-glutamyl transpeptidaseの研究
Biochemical and histochemical studies on variant γ-glutamyl transpeptidase in human gastric cancer
Creators
Oka Shinji
Source Identifiers
γ-glutamyl transpeptidase(GGT) that increase in gastric cancer was compared immunologically and biochemically with that from kidney. By means of the active inhibition test and the double immuno-diffusion test, it was observed that gastric cancer GGT had the similar immunological properties to kidney GGT. But in the studies of isoelectric focusing and Con-A column chromatography, gastric cancer GGT differed from kidney GGT in sialic acid contents and suger chain. On the other hand, histological study indicated that various mechanism, gene expression, proliferative state etc., was concerned with GGT appearance in gastric cancer. These data suggested that GGT was an useful enzyme to study enzyme transformation in tumorgenicity and that the study of suger chain meight develope a new method for the diagnosis of gastric cancer.
Languages
jpn
Resource Type
journal article
Publishers
山口大学医学会
Date Issued
1988-06
File Version
Not Applicable (or Unknown)
Access Rights
metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools
医学部