山口医学

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山口医学 Volume 46 Issue 1
published_at 1997-02

Polymorphism of apolipoprotein E and Occurrence of Psoriasis Vulgaris

尋常性乾癬患者におけるアポリポ蛋白E表現型の検討
Descriptions
We have studied polymorphism of apolipoprotein E (apoE) phenotype in sera from 100 patients with psoriasis vulgaris and 100 healthy controls. The phenotypes of apoE were determined by isoelectric focusing, which was followed by immunoblotting using an antibody specific for apoE. The frequency of apoE3/2 in psoriatic patients was significantly higher than those in controls. In addition, the statistical analysis revealed that there was an association between the allele for apoE2(ε2) and psoriasis vulgaris ( Pc<0.05 ).
Creator Keywords
尋常性乾癬
アポリポ蛋白E
等電点電気泳動
脂質代謝