Prognestic determinants of dilated cardiomyopathy

A total of 97 patients with dilated cardiomyopathy (DCM) were followed for 36±30 months to determine the prognostic determinants. 19 patients (20%) died, 11 patients due to heart filure, 7 patients due to sudden death, and 1 patent due to malignancy. The everall cumulative sruvival rate of 5 year was 75%. To ecaluated the prognosis of DCM, hemodynamics, wall motion abnormalitied, and shape of left ventricule were compared. 47 patients had diffeuse wall motion abnormailties (DWMA), 42 patients had segmental wall motion abnormalities (SWMA). Univerriate analysis revealed that Long-term survivous had SWMA, and lower filing pressure, ESVI, Time constant, and had higher MeanVcf, Peak Negative dP/dt, ΔSI, ESP/ESVI than Short-term survious. Multivariate linear regression analysis was used to determine which factors could predict the prognosis. The powerful predictors were (1) wall motion adnormalities (2) PCW (3) ESP/ESVI in its prder. It is concluded that DWMA was the most powerful prognostic determinant.