Endoscopic evaluation of high risk group in recurrence of duodenal ulcer

Dyeing endoscopy in combination with Methylene Blue (MB) and Congo Red (CR) was performed in 154 patients with duodenal ulcer (DU) scar. All the patients were followed periodically by dyeing endoscopy from 8 to 44 month. Incidence of the recurrence of DU was evaluated with the reference of the background factors, endoscopic findings and endoscopic dyeing patterns. Background factors (i.e. smoking habit, alcohol habit, stress and blood types) did not affect the recurrence of DU during maintenance therapy. No conventional endoscopic findings could predict the recurrence of DU. There were higher recurrence rates in patients shown poor absorption of MB and broad gastric secreting area. Preventive therapy for recurrence of duodenal ulcer guided by dyeing cndoscopy was estimated. Patients given maximum dose of antisecreting medicine showed expected outcome in its prevention. However patients who had discontinued or decreased the dosage of antisecreting agents did much higher recurrence rate of DU. It is concluded that