ラット胃の幽門部粘膜における腸管内分泌細胞とハンチンチン関連タンパク質HAP1の免疫組織化学的検討
Title
Immunohistochemical relationships of huntingtin-associated protein 1 with enteroendocrine cells in the pyloric mucosa of the rat stomach
ラット胃の幽門部粘膜における腸管内分泌細胞とハンチンチン関連タンパク質HAP1の免疫組織化学的検討
Degree
博士(医学)
Dissertation Number
医博乙第1101号
(2021-04-14)
Degree Grantors
Yamaguchi University
[kakenhi]15501
grid.268397.1
Creators
柳井 章江
Creator Keywords
huntingtin-associated protein 1, gastrin, somatostatin D cells
enterochromaffin cells
enterochromaffin-like cells
immunohistochemistry
Huntingtin-associated protein 1 (HAP1) is a neuronal cytoplasmic protein that is predominantly expressed in the brain and spinal cord. In addition to the central nervous system, HAP1 is also expressed in the peripheral organs including endocrine system. Different types of enteroendocrine cells (EEC) are present in the digestive organs. To date, the characterization of HAP1-immunoreactive (ir) cells remains unreported there. In the present study, the expression of HAP1 in pyloric stomach in adult male rats and its relationships with different chemical markers for EEC [gastrin, marker of gastrin (G) cells
Languages
eng
Resource Type
doctoral thesis
File Version
Not Applicable (or Unknown)
Access Rights
open access
Schools
大学院医学系研究科（医学）