The Study about the Function of Bile Epithelium in Secretin Test

セクレチン負荷試験における胆管上皮機能の検討

The Study about the Function of Bile Epithelium in Secretin Test

Creators 小田 正隆

Creators 福本 陽平

Creators 江崎 隆朗

Creators 天野 秀雄

Creators 相部 剛

Creators 安藤 啓次郎

Creators 坪田 若子

Creators 永富 裕二

Creators 川嶋 正男

Creators 沼 義則

Creators 播磨 一雄

Creators 渡辺 精四郎

Creators 野田 健一

Creators 富士 匤

Creators 児玉 隆浩

Creators 沖田 極

Creators 竹本 忠良

The bile epithelium cell was disturbed by 18 hours after administration of ANIT 80mg/kg, and secretin did not show any effects to bile secretion. Secretin test (S-test) was performed to the 10 cases of pancreatic head cancers, and in all of them, bile flow and bicarbonate level in the bile increased. The correlation between S-test and decreasing rate of the serum bilirubin was seen. Moreover, the correlation between the decreasing rate of the serum bilirubin and dilation of the bile duct was seen after PTCD. Therefore, it seemed that S-test might be reflection to the disturbance of the bile epithelium. It will be benefit to estimate the function of the bile epithelium.

[ISSN]0513-1731

[NCID]AN00243156