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Effect of non-thermal radio frequency burst-type electromagnetic field irradiation on the microcirculation and vascular contractility.

The bulletin of the Yamaguchi Medical School Volume 48 Issue 3-4 Page 35-45
published_at 2001-12
A020048000303.pdf
[fulltext] 942 KB
Title
Effect of non-thermal radio frequency burst-type electromagnetic field irradiation on the microcirculation and vascular contractility.
Creators Yoshimoto Yasunori
Source Identifiers
Creator Keywords
electromagnetic field hepatic blood flow vascular contractility endothelial function vascular smooth muscle
We investigated the effects of non-thermal radio frequency burst-type EMF irradiation on blood circulation of the rat in vivo. In order to investigate the cellular mechanisms, we also examined the direct effect of EMF irradiation on the contractility of oxgan-supplying artery and conduit artery and on endothelial function. EMF irradiation was achieved with an EMF generator coil used with 10-15 V peak-to-peak voltage. Changes in blood flow and blood mass in the rat liver were monitored with a laser Dopper flowmeter. Vascular contractility was measured in artery strips with a force transducer. Cytosolic Ca2+ concentration ([Ca2+] I) in endothelial cells was monitored in situ on the bovine aortic valve strips by front-surface fluorometry of fura-2. EMF irradiation induced slight increase of hepatic blood flow without affecting blood mass. However, EMF irradiation had no direct effect on the vascular contratility and on the [Ca2+]I levels in endothelial cells in situ. Our results indicate that EMF irradiation may play a minor role in the regulation of microcirculation.
Subjects
医学 ( Other)
Languages eng
Resource Type departmental bulletin paper
Publishers Yamaguchi University Graduate School of Medicine
Date Issued 2001-12
File Version Version of Record
Access Rights open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools 医学部