Nedaplatin /TS-1 chemotherapy and concurrent radiation therapy for oral cancer-preliminary experience

Novel anticancer drugs, platinum compound nedaplatin (CDGP) and 5-fluorouracil agent (TS-1), were applied to an oral squamous cell carcinoma patient having tumor located in right buccal mucosa. The tumor was 20 × 30 mm in size. Chemotherapy composed of CDGP 90 mg/m^2 (day 3) and TS-1 100 mg/body (day 1-5), and simultaneous radiation given by 1.8 Gy/day (day 1-5) was carried out. While the effect of this therapy was no change, trismus caused by tumor invasion was obviously ameliorated that had hampered QOL. The side effects were relatively severe : leukocytopenia, neutropenia, thrombocytopenia, and anorexia were grade 3

ネダプラチン

ティーエスワン

化学放射線併用療法

口腔扁平上皮癌

本文データは山口大学医学会の許諾に基づきCiNiiから複製したものである