The status quo of genetic diagnosis

Genetic diagnosis of infectious and hereditary diseases has recently been applied steadily to clinical laboratory test, but that of sporadic cancer, which was expected to give a big breakthrough for its early and exact detection, has been realized in only a limited number of diseases. Although genetic diagnosis is also expected to be of great help for early diagnosis and prevention of common polygenic disorders, it remains at the level of basic research. A new diagnostic method using DNA chip is now being exploited to realize a clinical application of genetic diagnosis of cancer. Accumulation of the information on DNA polymorphism and its effect on the gene function will be required to develop a new strategy for diagnosis of polygenetic disorders. In addition, it should be stressed that ethical consideration is essential to the progress of such genetic analyses.

遺伝子診断

がん

多因子性疾患

倫理問題

本文データは山口大学医学会の許諾に基づきCiNiiから複製したものである