A Case of Primary Splenic Malignant Lymphoma

Primary splenic malignant lymphoma (PSML) is a relatively rare entity: to date about 1 50 cases have been reported in Japan. We reported a case of PSML which occurred in a patient with hepatitis B virus infection. A 52-year-old man was accidentally diagnosed as having a high level of serum LDH, and hypoechoic tumors of the spleen by ultrasonography, conducted during a follow-up survey for chronic hepatitis. Enhanced CT revealed low density masses, and 67Ga scintigraphy revealed hot spots in the spleen. Based on these findings, the patient was diagnosed as having a PSML and underwent a laparoscope-assisted splenectomy. On cross section of the resected specimen, two yellowish white, nodular, and solid tumors were revealed. Histopathologically, these were diffuse, large cell type, B bell malignant lymphoma. According to international classification, the malignant grade corresponded to intermediate, so additional chomotherapy r surgery was performed.

脾原発悪性リンパ腫

67^Gaシンチグラフィ

脾摘出術