Effects of diazep (comelian) on aggressive behavior induced by clonidine

This study investigated the ability of dilazep (comelian) to prevent clonidine induced aggressive behavior in mice. Mice administered high doses of clonidine (20-50 mg/kg i.p.) exhibited aggressive behavior in dose dependent manner. Dilazep (5-20 mg/kg i.p.) dose-dependently inhibited the aggressive behavior induced by clonidine (50 mg/kg i.p.). Dilazep (2mg/kg i.p.), adenosine (10mg/kg i.p.), dipyridamole (10 mg/kg i.p.) or N^6-cyclohexyl adenosine (CHA