山口医学

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山口医学 Volume 35 Issue 4
published_at 1986-08

Autologous Bone Marrow Transplantation in CALLA Positive Acute Lymphoblastic Leukemia Using Bone Marrow Cells Treated in vitro with Monoclonal Antibodies Against Leukemic Blasts

CALLA 陽性急性リンパ性白血病における白血病細胞に対するモノクローナル抗体処理骨髄細胞を用いての自家骨髄移植
Nishimura Manabu
Shinohara Kenji
Yamada Katsunori
Azuno Yoichi
Tanaka Masafumi
Sasaki Hiroko
Seguchi Masato
Yaga Ken
Fujii Shinya
Ishida Yoji
Kaneko Toshio
Matsumoto Noboru
Descriptions
A nine years old girl of CALLA positive acute lymphoblastic leukemia was treated by autologous bone marrow transplantation (BMT) at the second remission by using autologous bone marrow cells, which was taken at the first remission and was treated with the monoclonal antibodies against leukemic blasts in vitro. The recovery of reticulocyte and granulocyte after BMT was prompt, but the platelet production was depressed, and the patient died of intraabdominal hemorrhage 28 days after BMT.