A Study of Serum Immunoglobulin in Epileptic Patients

Recently there have been many reports about immunological abnormalities induced by antiepileptics. We measured the serum immunoglobulin levels in 41 epileptic patients and compared the mean serum levels between the used drugs and the types of epilepsy. As the result, no immunoglobulin levels fell into abnormal range in the administration of 4 drugs - diphenylhydantoin (DPH), phenobarbital (PB), sodium valproate (VPA) and carbamazepine (CBZ) - and in the primary generalized epileptic patients.