山口医学

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山口医学 Volume 29 Issue 2
published_at 1980-06

Pathological Study on Amyloidosis Farm Variability in Experimental Murine (C_3H/He) Amyloidsis

アミロイド症の病理学的研究 各種動物繁殖場別によるマウス(C_3H/H)のアミロイド症の発生比較
Hara Takuji
Descriptions
Incidence of experimrntal amyloidosis in the identaical strain mice (C_3H/He) derived from five different farms (Shizuoka, Funahashi. Clea, Seiwa and Chales) was composed. Complete Freund's Adjuferent mixed with Mycrobacterium was used as an amyloid-inducing agent, and ten days after a single injection amyloid deposition in the histologically examined. The following results were observed. 1. Incidence of amyloidosis was the highest in the mice from Shizuoka and Seiwa farm (100%), followed by the mice from Clea farm (75%). The mice from the other two farms (Charles and Funahashi) showed the lowest incidence (58%)…