山口医学

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山口医学 Volume 27 Issue 1
published_at 1978-03

Effwct of 2-Mercaptopropionyl Glycine (MPG) on Radiation-Induced Mitotic Delay in Cultured Mammalian Cell (L-5)

放射線による細胞分裂遅延に対する2-Mercaptopropionyl Glycine(MPG) の効果
Kawasaki Syoji
About This Article
Descriptions
Effect of 2-Marcaptopropionyl Glycine (MPG) on radiation-induced mitotic delay in cultured manmalian cell (L-5) was studied. The mitotic delay induced by irradiation of 200 rads was protected with treatment of MPG (20-100mM). A recovery curves of mitotic index became steep with increasing of MPG concentration. But the mitotic delay time was not shortened by MPG. On the basis of these data, the mechanisms of the radioprotective action of MPG were discussed.
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