The bulletin of the Yamaguchi Medical School

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EISSN：2758-5441

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The bulletin of the Yamaguchi Medical School Volume 43 Issue 3-4
published_at 1996-12

Hepatic fibrogenesis and carcinogenesis

Hepatic fibrogenesis and carcinogenesis
Sakaida Isao
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A020043000301.pdf
About This Article
Descriptions
The stellate cell plays a central role in liver fibrosis in human liver diseases as well as in experimantal animal models. Direct prevention of liver fibrosis by a newly synthesized proly 4-hydroxylase inhibitor (HOE 077) reduced the number of preneoplastic lesions in rat liver. Fibrosupperession may limit the development of hepatic neoplasms.
Creator Keywords
fibrosis
stellate cell
proly 4-hydroxylase inhibitor
preneoplastic lesion
glutathione S-transferase placental form
choline-deficient L-amino acid-defined diet
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