The bulletin of the Yamaguchi Medical School

Continued by:Medical Science & Innovation
EISSN:2758-5441

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The bulletin of the Yamaguchi Medical School Volume 39 Issue 3-4
published_at 1992-12

Magnetic resonance image in probable Alexander's disease

Magnetic resonance image in probable Alexander's disease
Yamamoto Kiyoshi
Morimatsu Mitsunori
Ukita Takeshi
Yamada Michio
fulltext
1.48 MB
A020039000306.pdf
Descriptions
We report the case of a 14-year-old girl with suspected Alexander's disease. Magnetic resonance imaging of the brain showed decreased intensity in the frontal white matter on T1-weighted sequences, and an increasd intensity on T2-weighted images. T1-weighted sequences demonstrated an increased attenuation of the basal ganglia, occipital lobes, cerebellum and brainstem. T2-weighted images showed a decreased intensity of the basal ganglia and brainstem. Magnetic resonance imaging is a useful adjunct in establishing a premortal diagnosis of Alexander's disease without brain biopsy.
Creator Keywords
Alexander's disease
Magnetic resonance imageing
Single photon emission computed tomography(SPECT)