The bulletin of the Yamaguchi Medical School

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The bulletin of the Yamaguchi Medical School Volume 37 Issue 3-4
published_at 1990-12

Prolonged Neuromuscular and Cardiovascular Effects of Succinylcholine in a Patient Homozygous for the Silent Gene

Prolonged Neuromuscular and Cardiovascular Effects of Succinylcholine in a Patient Homozygous for the Silent Gene
Yamamoto Midori
Wakuta Kayoko
Oshita Shuzo
Hiraoka Izumi
Takeshita Hiroshi
Matsuno Youko
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A020037000309.pdf
Descriptions
We investigated the duration of cardiovascular as well as neuromuscular effects of succinylcholine in a patient homozygous for silent gene. The patient remained totally apneic for about 30 min, and the train-of-four ratio was 0.82 even at 150 min after succinycholine 1 mg/kg ⅳ. These results may suggest that cardiovascular and neuromuscular effects of succinylcholine are both prolonged in a patient homozyfous for silent gene.
Creator Keywords
Succinylcholine
Catecholamines
Abnormal Pseudocholinesterase