A SIMPLE PROCEDURE FOR THE ESTIMATIONS OF SERUM CHOLINESTERASE APPLICATION TO ROUTINE CLINICAL BIOCHEMISTRY

A simple hydrogen- ionometric procedure for estimation of the serum cholinesterase by means of a comparator with phenol red as indicator is presented. This was compared with Ammon's and Mihel's methods to check its accutacy and reliability, and it was confirmed that the procedure gave estimations in the subnormal range of the serum cholinesterase activity with an accuracy satisfactory for clinical purposes, although it was a little insensitive to the detection of its variation in the normal and supernormal range. The procedure was thought to be suitable for the clinical biochemistry that was obliged to deal with a large number of morbid materials within a short period of time, because it was simple in technique and required no expensive instruments.