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ラット胃の幽門部粘膜における腸管内分泌細胞とハンチンチン関連タンパク質HAP1の免疫組織化学的検討

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Title
Immunohistochemical relationships of huntingtin-associated protein 1 with enteroendocrine cells in the pyloric mucosa of the rat stomach
ラット胃の幽門部粘膜における腸管内分泌細胞とハンチンチン関連タンパク質HAP1の免疫組織化学的検討
Degree 博士(医学) Dissertation Number 医博乙第1101号 (2021-04-14)
Degree Grantors Yamaguchi University
[kakenhi]15501 grid.268397.1
Creators 柳井 章江
Creator Keywords
huntingtin-associated protein 1, gastrin, somatostatin D cells enterochromaffin cells enterochromaffin-like cells immunohistochemistry
Huntingtin-associated protein 1 (HAP1) is a neuronal cytoplasmic protein that is predominantly expressed in the brain and spinal cord. In addition to the central nervous system, HAP1 is also expressed in the peripheral organs including endocrine system. Different types of enteroendocrine cells (EEC) are present in the digestive organs. To date, the characterization of HAP1-immunoreactive (ir) cells remains unreported there. In the present study, the expression of HAP1 in pyloric stomach in adult male rats and its relationships with different chemical markers for EEC [gastrin, marker of gastrin (G) cells
Languages eng
Resource Type doctoral thesis
File Version Not Applicable (or Unknown)
Access Rights open access
Schools 大学院医学系研究科(医学)