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Okuda Shinichi

Affiliate Master Yamaguchi University

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We investigated the relationship between myocardial oxidative stress and cardiac sympathetic hyperactivity in patients with takotsubo cardiomyopathy (TC) compared with acute anteroseptal myocardial infarction (AMI). Methods: In 10 TC patients and 10 AMI patients, electrocardiogram, echocardiography, cardiac catheterization were conducted, and plasma catecholamines and urinary (U) 8-hydroxy-2’-deoxyguanosine (8-OHdG) as a marker of oxidative DNA damage were taken for one week from onset. Results: On admission, the coronary sinus (CS) had significantly higher norepinephrine (NE) and 8-OHdG levels than the aortic root (Ao) and peripheral blood vessels. Circulating catecholamines in TC patients tended to be higher than those in AMI patients
日本臨床 Volume 69 Issue 増刊9 pp. 595 - 604
published_at 2011-11
Creators : 奥田 真一 矢野 雅文 Publishers : 日本臨牀社
European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology Volume 13 Issue 1 pp. 29 - 36
published_at 2011-01
Creators : Kobayashi Shigeki Susa Takehisa Tanaka Takeo Wada Yasuaki Okuda Shinichi Doi Masahiro Nao Tomoko Yoshiga Yasuhiro Yamada Jutaro Okamura Takayuki Ueyama Takeshi Kawamura Syuji Yano Masafumi Matsuzaki Masunori Publishers : Elsevier | European Society of Cardiology
Clinical Calcium Volume 23 Issue 4 pp. 471 - 480
published_at 2013-04
Creators : Okuda Shinichi Yano Masafumi Publishers : 医薬ジャーナル社
Circulation Journal Volume 77 Issue 7 pp. 1684 - 1686
published_at 2013
Creators : Okuda Shinichi Yano Masafumi Publishers : Japanese Circulation Society
Cardiology (Switzerland) Volume 127 Issue 2 pp. 105 - 113
published_at 2014-01
Creators : Kobayashi Shigeki Murakami Wakako Myoren Takeki Tateishi Hiroki Okuda Shinichi Doi Masahiro Nao Tomoko Wada Yasuaki Matsuzaki Masunori Yano Masafumi Publishers : Karger