CALLA 陽性急性リンパ性白血病における白血病細胞に対するモノクローナル抗体処理骨髄細胞を用いての自家骨髄移植

Autologous Bone Marrow Transplantation in CALLA Positive Acute Lymphoblastic Leukemia Using Bone Marrow Cells Treated in vitro with Monoclonal Antibodies Against Leukemic Blasts

Creators Nishimura Manabu

Creators Shinohara Kenji

Creators Yamada Katsunori

Creators Azuno Yoichi

Creators Tanaka Masafumi

Creators Sasaki Hiroko

Creators Fujii Yasuhiko

Creators Seguchi Masato

Creators Yaga Ken

Creators Fujii Shinya

Creators Ishida Yoji

Creators Kaneko Toshio

Creators Matsumoto Noboru

A nine years old girl of CALLA positive acute lymphoblastic leukemia was treated by autologous bone marrow transplantation (BMT) at the second remission by using autologous bone marrow cells, which was taken at the first remission and was treated with the monoclonal antibodies against leukemic blasts in vitro. The recovery of reticulocyte and granulocyte after BMT was prompt, but the platelet production was depressed, and the patient died of intraabdominal hemorrhage 28 days after BMT.

[ISSN]0513-1731

[NCID]AN00243156