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フルテキストURLA050065000103.pdf ( 900.6KB ) 公開日 2018-08-22
タイトルImmunoglobulin-resistant kawasaki disease associated with human parvovirus B19 infection
作成者Iida, Yasunori
Hasegawa, Shunji
Korenaga, Yuno
Okada, Seigo
Suzuki, Yasuo
Hirano, Reiji
Ohga, Shouichi
作成者ヨミイイダ, ヤスノリ
ハセガワ, シュンジ
コレナガ, ユノ
オカダ, セイゴ
スズキ, ヤスオ
ヒラノ, レイジ
オオガ, ショウイチ
作成者別表記飯田, 恵庸
長谷川, 俊史
是永, 優乃
岡田, 清吾
鈴木, 康夫
平野, 玲史
大賀, 正一
作成者所属山口大学大学院医学系研究科(医学)
内容記述(抄録等)A 23-month-old female presented with 6 full symptoms of Kawasaki disease (KD) and thrombocytopenic purpura of the lower extremities. Repeated intravenous immunoglobulin normalized the platelet counts, but not improved the activity of intractable KD. Primary infection of human parvovirus B19 (B19V) was determined at the diagnosis of KD based on the hypocomplementemia and the positive tests for anti-B19V IgM antibody. Infliximab therapy led to the complete resolution with no atypical or persistent infection of B19V, or coronary artery lesions. This is the first report of intravenous immunoglobulin-resistant KD associated with the primary infection of B19V. Successful treatment of the B19V-associated KD case suggested a clinical utility of the standard rescue infliximab for the treatment of intravenous immunoglobulin-resistant KD, possibly with concurrent infection. Abbreviations: B19V: human parvovirus B19, IVIG: ntravenous immunoglobulin, KD: Kawasaki disease
本文言語eng
著者キーワードinfliximab
Kawasaki disease
parvovirus B19
virus reactivation
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
65
1-2
開始ページ21
終了ページ25
発行日2018
著者版/出版社版出版社版
リポジトリIDA050065000103
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A050065000103