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フルテキストURLA020035000304.pdf ( 267.6KB ) 公開日 2010-04-19
タイトルClinical Application of Measuring Serum Fructosamine as an Index of Glycemic Control in Diabetic Patients
作成者Nagasaka, Yuji
Fujii, Shinya
Yaga, Ken
Matsumura, Shigekazu
Kaneko, Toshio
作成者ヨミナガサカ, ユウジ
フジイ, シンヤ
ヤガ, ケン
マツムラ, シゲカズ
カネコ, トシオ
作成者所属山口大学医学部
内容記述(抄録等)Measurement of serum fructosamine is a new method for the quantification of glycated serum proteins. We examined the clinical application of measuring serum fructosamine as an index of glycemic control in diabetic patients. Serum fructosamine had good correlation with mean fasting plasma glucose obtained 0-3 weeks before the fructosamine measurement and had best correlation with that obtained 1 week before the measurement (r=0.531, p<0.001). Correlations with mean fasting plasma glucose obtained 4 week before the measurement (r=0.407, p<0.1) or hemoglobin A1 at the nearly same sampling time (r=0.306, p<0.2)were not significant. The patients tested were divided into 4 groups according to diabetic control evaluted from mean fasting plasma glucose obtained 1week before the fructosamine measurement ; an excellent group (<120 mg/dl) ; a good grop (121-140 mg/dl) ; a fair group (141-160 mg/dl) ; a poor group (>161 mg/dl). Mean value of serum fructosamine in an excellent group was significantly higher than that in healht controls (p<0.05), and increased according to worseing of glycemic control, and that in a poor group was significantly higher than that of an exellent group (p<0.001). These results suggested that measurement of serum fructosamine is useful as amedum term (0-3 weeks) index of glycemic control in diabetic patients, especially who have had a rapid flucuation in glycemic control for a couple of weeks.
本文言語eng
著者キーワードSerum functosamine
Hemoglobin A1
Glycemic control
Diabetic patients
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
35
3-4
開始ページ59
終了ページ62
発行日1988-12
著者版/出版社版出版社版
リポジトリIDA020035000304
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020035000304