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タイトルOvarian follicular development in the unilateral ovariectomized rat
作成者Kagabu, Satosi
Umezu, Motoaki
作成者ヨミカガブ, サトシ
ウメズ, モトアキ
作成者別表記利部, 聰
梅津, 元昭
作成者所属山口大学農学部
内容記述(抄録等)Background and Aims: Following unilateral ovariectomy, the contralateral ovary underwent hypertrophy and the number of ovulations remained unchanged. The aim of the present study was to elucidate the mechanism, which occurred by this compensation, through examination of ovarian follicular development in operated rats. Methods: Rats were examined 1-8 weeks post unilateral operation. The ovaries were serially sectioned. All sections were examined and the size of each follicle was measured. Results: Large follicles soon recovered after surgery, but it took 5 weeks for small and medium-sized follicles to recover. The rate of atresia at the 'critical point' was 31.1% in unilateral ovariectomized animals and 73.9% in the sham-operated rats. Conclusions: These findings showed that in operated rats, the recovery of the number of follicles varied depending on the size of the follicle. Compared with the control animals, approximately twice as many large healthy follicles were saved from atresia at the 'critical point', producing a compensatory increase in the ovulation number (P < 0.01).
本文言語eng
著者キーワードatretic follicle
Graafian follicle
ovarian follicle
rats
unilateral ovariectomy
資料タイプtext
出版者Blackwell
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN1445-5781
NCIDAA11706516
掲載誌名Reproductive medicine and biology
4
1
開始ページ89
終了ページ92
発行日2005-03
DOIinfo:doi/10.1111/j.1447-0578.2005.00091.x
関連情報URL(IsPartOf)http://www.blackwell-synergy.com/loi/rmb?cookieSet=1
著者版/出版社版その他
リポジトリID2008010075
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/2008010075