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タイトルFollicular development and induction of ovulation with human chorionic gonadotropin in the pregnant rat
作成者Kagabu, Satosi
Umezu, Motoaki
作成者ヨミカガブ, サトシ
ウメズ, モトアキ
作成者別表記利部, 聰
梅津, 元昭
作成者所属山口大学農学部
内容記述(抄録等)Aims: The number of ovarian follicles and ovulations after human chorionic gonadotrophin (hCG) was given at various doses during pregnancy were investigated in rats. Methods: On designated days of pregnancy, rats were injected with hCG at 13.00 hours and the number of ova were observed. The same rats were then killed at 13.00 hours the next day. The ovaries were cut into complete sections. All sections were observed and the size of each follicle was measured. Results: The number of large (≧550 μm), healthy, non-atretic follicles (Graafian follicles) ranged from 1.5 to 11 during pregnancy. Ovulation was induced in rats at any stage of pregnancy with intramuscular injections of 40 or 50 IU hCG, but 10 IU had no effect and 20 or 30 IU had an incomplete effect. The number of ovulations after 40 IU hCG was 2-12 and there was not a significant difference between the number of ovulations and the number of large, healthy follicles at any point in the pregnancy. Conclusion: Graafian follicles existed through the pregnancy. Results suggest that although hCG induces ovulation in large ovarian follicles (≧550 μm) during pregnancy, the responsiveness to hCG is lower than in recurrent estrus-stage rats.
本文言語eng
著者キーワードgraafian follicle
ovarian follicle
ovulation
pregnancy
rats
資料タイプtext
出版者Blackwell
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN1445-5781
NCIDAA11706516
掲載誌名Reproductive medicine and biology
3
4
開始ページ201
終了ページ204
発行日2004-12
DOIinfo:doi/10.1111/j.1447-0578.2004.00071.x
関連情報URL(IsPartOf)http://www.blackwell-synergy.com/loi/rmb?cookieSet=1
著者版/出版社版その他
リポジトリID2008010074
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/2008010074