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フルテキストURLA020032000112.pdf ( 10.9MB ) 公開日 2010-04-19
タイトルQuantitative Evaluation of Left Ventricular Relaxation by Apexcardiogram in Coronary Artery Disease.
作成者Sugihara, Nobuyuki
Kumada, Toshiaki
Ozaki, Masaharu
Okayama, Akira
Matsuzaki, Masanori
Matsuda, Yasuo
Kusukawa, Reizo
作成者ヨミスギハラ, ノブユキ
クマダ, トシアキ
オザキ, マサハル
オカヤマ, マサハル
マツザキ, マサノリ
マツダ, ヤスオ
クスカワ, レイゾウ
作成者所属山口大学医学部
内容記述(抄録等)To assess non-invasively whether the location,extent and severity of left ventricular (LV) contraction abnoumalities affect LV relaxation, we studied apexcardiogram (ACG) in 48 patients with coronary artery disease (CAD) of over 75% luminar stenosis and 16 control subjects under basal conditions within a week before cardiac catheterization. Asynergy of LV wall motion was classified on the basis of AHA committee ventriculography reporting system. The patients consisted of control sudjects [Group I:n=16]and the patients with CAD of one-vessel disease in right coronary artery or left circumflex coronary artery stenosis[Group II ; n=16],of one-vessel disease in left anterior descending coronary artery stenosis [Group III ; n=20] and of three-vessel disease associated with general hypokinesis[Group IV ; n=12]. ⊿t was defined as the time interval between the anortic compoment of the second heart sound heart sound (A2) and the 50% height of ACG deflection from the end-systolic shoulder of the onest of A2 to the nadir of ACG (O-point), during isovolumic relaxation period. ⊿t was significantly prolonged in Group III (60±12 msec, P<0.05) and Group IV (73±12 msec, P<0.01) comparted to in group I (51±11 msec). There were good correlations between ⊿t and LV peak negative dP/dt(r=-0.44, P<0.01) and between ⊿t and time constant of isovolumic LV presure decay (r=0.54, P<0.01). ⊿t reflects the impairment of LV relaxation, and then the extent and/or severity rather than the locality of LV wall motion abnormalities increased ⊿t,probadly due to a global impairment of LV relaxation.
本文言語eng
著者キーワードLV relaxation
ACG
Ischemic heart disease
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
32
1
開始ページ89
終了ページ99
発行日1985-12
著者版/出版社版出版社版
リポジトリIDA020032000112
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020032000112