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フルテキストURLフルテキストリンクなし
タイトルImplication of activation of intraperitoneal macrophages with bio-degradable microspheres
作成者Okawa, T.
Ichimal, H.
Ishida, T.
Kawata, M.
Kagabu, S.
Mamba, K.
Makita, T.
作成者ヨミカガブ, サトシ
作成者別表記利部, 聰
Kagabu, Satoshi
作成者所属山口大学農学部
内容記述(抄録等)To estimate the possibility that biological degradable starch microspheres (DMS) activate abdominal or intraperitoneal macrophages (IMP), two sizes of DMS (Spherex, Pharmacia, Sweden) were injected into the peritoneum of the ICR mice of 4 to 8 weeks of age. Three days after the injection, peritoneal fluid was collected and incubated for one hour at 37℃ under 5% CO_2. The cells which adhered to the petri dish were IMP, to which DMS was added for 18 hrs. The cultured IMP were observed by scanning electron microscope (SEM) and the ratio of the active type to the total number of IMP was counted as an index of the effect of DMS to IMP. The activation effect of DMS on the incubated IMP was significant in the group which was cultured with 2μm DMS after the 45μm DMS injection. That indicated the possible DMS function as a potential IMP activating factor (MAF).
本文言語eng
資料タイプtext
出版者Elsevier
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0309-1651
NCIDAA00600025
掲載誌名Cell biology international reports
13
6
開始ページ547
終了ページ553
発行日1989-06
DOIinfo:doi/10.1016/0309-1651(89)90101-X
関連情報URL(IsPartOf)http://www.sciencedirect.com/science/journal/03091651
著者版/出版社版その他
リポジトリID2008010051
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/2008010051