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フルテキストURL2008010276.pdf ( 1003.3KB ) 公開日 2010-04-16
タイトルAge-related changes of bone mineral density and microarchitecture in miniature pigs
作成者Inui, Azusa
Itamoto, Kazuhito
Takuma, Tetsuya
Tsutsumi, Hideki
Tanigawa, Manabu
Hayasaki, Mineo
Taura, Yasuho
Mamba, Kouichi
作成者ヨミイヌイ, アズサ
イタモト, カズヒト
タクマ, テツヤ
ツツミ, ヒデキ
タニガワ, マナブ
ハヤサキ, ミネオ
タウラ, ヤスホ
マンバ, コウイチ
作成者別表記板本, 和仁
田浦, 保穗
早崎, 峯夫
作成者所属山口大学農学部
内容記述(抄録等)Bone mineral density (BMD), distribution of its density and bone histomorphometric parameters were evaluated in lumbar vertebra of normally growing miniature pigs. The fourth lumbar vertebra (L4) of the Gottingen miniature pig were used in this cross-sectional study in vitro. The BMD of the miniature pig was similar to that of humans in tendency of gender differences and some growth patterns during puberty. In these regards this animal appears useful as a model for human bone study. However, the trabecular and cortical BMDs of lumbar spine were extremely high value (399.43 ± 26.36 mg/cm^3 in female trabeculae; 973.06 ± 69.55 mg/cm^3 in female cortical bone; 419.04 ± 34.84 mg/cm^3 in male trabeculae; 1038.81 ± 125.72 mg/cm^3 in male cortical bone in pigs 30 months or more). Furthermore, histomorphometric analysis yielded values that were remarkably different from those found in humans. From these results, it was revealed that miniature pig had a higher bone mass and denser trabecular network than human, indicating that its bone is probably stronger. Therefore, care should be taken in choosing the miniature pig as a bone study model.
本文言語eng
著者キーワードbone mineral density
histomorphometric analyses
lumbar spine
miniature pig
資料タイプtext
ファイル形式application/pdf
出版者日本獣医学会
出版者ヨミニホン ジュウイ ガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0916-7250
NCIDAA10796138
掲載誌名The Journal of veterinary medical science
66
6
開始ページ599
終了ページ609
発行日2004
DOIinfo:doi/10.1292/jvms.66.599
関連情報URL(IsPartOf)http://www.jstage.jst.go.jp/browse/jvms/-char/ja/
著者版/出版社版出版社版
リポジトリID2008010276
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/2008010276