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フルテキストURL2007020199.pdf ( 3.2MB ) 公開日 2010-04-16
タイトルQuantitative and morphological studies on the influence of zinc deficiency on the liver of pregnant rats
タイトルヨミアエン ケツボウ ノ ニンシン ラット カンゾウ ニオケル テイリョウテキ オヨビ ケイタイガクテキ ケンキュウ
タイトル別表記亜鉛欠乏の妊娠ラット肝臓における定量的および形態学的研究
作成者Mamba, Kouichi
Taniguchi, Kazuyuki
Kagabu, Satoshi
Makita, Takashi
作成者ヨミマンバ, コウイチ
タニグチ, カズユキ
カガブ, サトシ
マキタ, タカシ
作成者別表記萬場, 光一
谷口, 和之
利部, 聰
牧田, 登之
作成者所属山口大学農学部
内容記述(抄録等)The effect of zinc deficiency on trace metals in the liver, spleen, kidney, pancreas and duodenum was investigated in the control and zinc-deficient rate at 17 days and 20 days of pregnancy. Zinc-deficient rats fell into limosis after 5 days of pregnancy. The contents of zinc, iron, copper and manganese in the maternal tissues were measured by colorimetry with 5NPPF. The morphological changes of the liver were observed by light and electron microscopy. The contents of zinc in the pancreas and duodenum were less in the zinc-deficient group than in the control at both 17 days and 20 days of pregnancy. The contents of the copper and manganese in the liver, kidney, pancreas, duodenum and spleen, however, were not significantly different from the control. The contents of iron in the liver, spleen and kidney in the deficient group increased greatly at 17 days and 20 days of pregnancy compared with the control group. The combination rate of transferrin with iron also increased significantly in the deficient group. Staining with Berlin blue or Turnbull's blue showed intense reaction to iron around the interlobular connective tissue of the liver in the zinc deficient group at 20 days; of pregnancy. Ultrastructurally, the liver of the zinc-deficient rats showed the decrease of glycogen granules and increase of lipid-like granules and lysosomes with various sizes and electron densities. These findings suggest that zinc deficiency causes the increase of iron contents in the various organs during pregnancy, and that there is an intimate interrelationship between zinc and iron in the metabolism of iron during pregnancy.
本文言語eng
著者キーワードiron content
pregnancy
rat liver
zinc deficiency
資料タイプtext
ファイル形式application/pdf
出版者日本獣医学会
出版者ヨミニホン ジュウイ ガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0021-5295
NCIDAA10521639
掲載誌名Japanese journal of veterinary science
51
3
開始ページ566
終了ページ573
発行日1989
関連情報URL(IsPartOf)http://www.journalarchive.jst.go.jp/japanese/jnltop_ja.php?cdjournal=jvms1939
著者版/出版社版出版社版
リポジトリID2007020199
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/2007020199