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フルテキストURLA020028000307.pdf ( 538.1KB ) 公開日 2010-04-19
タイトルComputerized Transverse Axial Tomography in Epilepsy
作成者Kobashi, Kenshi
作成者ヨミコバシ, ケンシ
作成者所属山口大学医学部
内容記述(抄録等)The effects of hypotension induced by trimethaphan (TMP) or nitroprusside (NTP) together with controlled hemorrhage on cerebral electrical activity, cerebrospinal fluid pressure and systemic circulatory and metabolic variables were measured in 10 mongrel dogs anesthetized with halothane (end-tidal, 0.88±0.03%). Induced hypotension was maintained at cerebral perfusion pressure of 45 mmHg for 45 min and then at 30 mmHg for 45 min. In 5 TMP dogs, there were signicant decreases in EEG-power and slowing of peak power frequency from the frontal area, but not from the occipital area. The cerebrospinal fluid pressure did not change significantly except for an increase during induction stage of hypotension. In 5 NTP dogs, there were no significant changes in EEG-power and peak power frequency throughout the study from both frontal and occipital areas, but cerebrospinal fluid pressure increased significantly. With both drugs, an increase in glucose, lactate and lactate pyruvate ratio, and a decrease in Pao_2 were more pronounced at 30 mmHg than 45mmHg. With NTP, there were sustained increases in lactate and lactate pyruvate ratio even after restoration of arterial pressure. The same magnitude and duration of decrease in cerebral perfusion pressure induced by either TMP or NTP produced different effects on cerebral and systemic function.
本文言語eng
著者キーワードEpilesy; Computerized tomography (CT scan)
EEG
主題医学
資料タイプtext
ファイル形式application/pdf
出版者Yamaguchi University Graduate School of Medicine
NII資料タイプ紀要論文
ISSN0513-1812
NCIDAA00594272
学内刊行物(紀要等)The bulletin of the Yamaguchi Medical School
掲載誌名The bulletin of the Yamaguchi Medical School
掲載誌名別表記山口医科大学紀要
28
3-4
開始ページ127
終了ページ134
発行日1981-12
著者版/出版社版出版社版
リポジトリIDA020028000307
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/A020028000307