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タイトル多分化能を示したepithelioid sarcomaの1例
タイトルヨミタブンカ ノウ オ シメシタ epithelioid sarcoma ノ 1レイ
タイトル別表記A Case of Epithelioid Sarcoma Displaying Pluripotential Differentiation
作成者西山, 和光
麻上, 千鳥
山田, 健一
作成者ヨミニシヤマ, カズミツ
アサガミ, チドリ
ヤマダ, ケンイチ
作成者別表記Nishiyama, Kazumitsu
Asagami, Chidori
Yamada, Kenichi
作成者所属山口大学医学部
内容記述(抄録等)A light and electron microscopic study was performed on surgical materials of an epithelioid sarcoma from a 47-year-old man who had diffuse induration in the left arm for 10 years. Surgery and immun ochemical therapy were of little help and he died in a course of one year with pulmonary metastases. Light microscopically, the tumor was composed of nodular proliferation of epithelioid cells in the main, but in some areas it showed pluripotential differentiation towards osteoblasts, rhabdomyoblasts, angioblasts, spindle cells and foamy cells. Electron microscopically, tumor cells in the epithelioid island contained in their cytoplasm abundant microfilaments showing tonofibril-like arrangement, which suggest that they are epithelial in origin, but they had neither desmosome nor basal lamina. Spindle cells showed ultrastructural features similar to those of fibroblasts, and foamy cells to those of fat cells. The biphasic pattern with epithelioid cells and spindle cells is consistent with the reported cases of epithelioid sarcoma, but pluripotential differentiation has not yet been described. The finding of the pluripotential differentiation indicates that the tumor has the features similar to malignant mesenchymoma.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
31
4
開始ページ393
終了ページ401
発行日1982-08
著者版/出版社版その他
リポジトリIDB030031000406
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030031000406