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タイトル妊娠ラットにおける子宮の黄体機能抑制効果とその作用時期
タイトルヨミニンシン ラット ニ オケル シキュウ ノ オウタイ キノウ ヨクセイ コウカ ト ソノ サヨウ ジキ
タイトル別表記The Critical Period and for the Nongravid Uterus to Induce Luteolysis in Pregnant Rats
作成者南條, 和也
作成者ヨミナンジョウ, カズヤ
作成者別表記Nanjo, Kazuya
作成者所属山口大学医学部
内容記述(抄録等)The present paper demonstrates the critical time of the nongravid uterus to induce luteolysis in pregnant rats. On day 7 of pregnancy, the number of conceptuses was adjusted to one by aspirating all but the single conceptus (Asp group). The nongravid part of the uterus was then removed by partial-hysterectomy on day 7, 8, 9 or 12 of pregnancy (Asp-Ph7, Asp-Ph8, Asp-Ph9 or Asp-Ph12 group). The Asp-Ph7 group showed significantly higher serum progesterone levels than Asp group on day 15 and 17, while the progesterone levels in the Asp-Ph9 or Asp-Ph12 group remained at or below the value of day 12 on days 15 and 17. Both the Asp and Asp-Ph7 groups, which were hypophysectomized and totally hysterectomized on day 12, responded to the treatment with estradiol plus placental luteotrophins as well, and showed rather higher serum progesterone levels in the Asp group than the Asp-Ph7 group. It was concluded that the nongravid uterus would act between days 7 and 9 of pregnancy to prevent the rise in serum progesterone levels which were normally observed after day 12 of pregnancy, which would be mediated through the pituitary.
本文言語jpn
主題医学
資料タイプtext
出版者山口大学医学会
出版者ヨミヤマグチ ダイガク イガッカイ
NII資料タイプ学術雑誌論文
査読の有無査読あり
ISSN0513-1731
NCIDAN00243156
学内刊行物(紀要等)山口医学
掲載誌名山口医学
35
6
開始ページ375
終了ページ379
発行日1986-12
著者版/出版社版その他
リポジトリIDB030035000607
地域区分山口大学
URIhttp://www.lib.yamaguchi-u.ac.jp/yunoca/handle/B030035000607